Journal of Drug Design and Medicinal Chemistry

Volume 11, Issue 2, June 2025

  • Review Article

    A Review of Current Trends and Advances in Analytical Methods for Determination of ACE Inhibitors Combinations with Hydrochlorothiazide

    Imad Osman Abu Reid*, Sayda Mohamed Osman, Somia Mohammed Bakheet

    Issue: Volume 11, Issue 2, June 2025
    Pages: 13-30
    Received: 31 January 2025
    Accepted: 28 February 2025
    Published: 24 May 2025
    DOI: 10.11648/j.jddmc.20251102.11
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    Abstract: Background. Hypertension is a leading risk factor for cardiovascular diseases, contributing significantly to global morbidity and mortality. Combination therapy using an angiotensin-converting enzyme (ACE) inhibitor with a diuretic offers distinct advantages over monotherapy in managing hypertension. With the increasing use of fixed-dose combinatio... Show More