Abstract: Malaria is a public health problem that has affected many countries across the continent. To address this problem, a malaria mathematical model on assessing the impact of strong and weak immunity was investigated. In addition to that drug resistance and intensive treatment analysis was also analyzed between human and mosquito population by the use of appropriate and standard procedures. A malaria model was developed where strong immunity, and weak immunity parameters were incorporated. A variable of drug resistance was also incorporated to describe the rates of transmission of human and mosquito populations. The basic reproductive number was derived using the Next Generation Matrix Method. The stability of the basic reproductive number was checked by use of the Jacobian Matrix. The disease Free equilibrium was found to be locally asymptotically stable as the basic reproductive number is less than one and unstable if greater than one. The results were found that increased immunity, and intensive treatment helped reduce the number of infections and increased recoveries. This study will be useful to the government and non governmental organizations because they will do intensive treatment to those who have resistance malaria infections and low immunity. The government will also give immune boosters so that drug resistance can stop and increase immunity hence leading to high recoveries. The mathematical malaria modelers will use this study as reference in their research.Abstract: Malaria is a public health problem that has affected many countries across the continent. To address this problem, a malaria mathematical model on assessing the impact of strong and weak immunity was investigated. In addition to that drug resistance and intensive treatment analysis was also analyzed between human and mosquito population by the use ...Show More