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LncRNAs: The Ideal Composer of the Melody for Life

Received: 18 May 2016     Accepted: 6 June 2016     Published: 30 June 2016
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Abstract

Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.

Published in Biomedical Sciences (Volume 2, Issue 2)
DOI 10.11648/j.bs.20160202.11
Page(s) 11-15
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Long Noncoding RNA, Human Diseases, Epigenetic, Transcription, Post-Transcription

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Cite This Article
  • APA Style

    Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. (2016). LncRNAs: The Ideal Composer of the Melody for Life. Biomedical Sciences, 2(2), 11-15. https://doi.org/10.11648/j.bs.20160202.11

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    ACS Style

    Qingyu Cheng; Shengwei Ke; A. R. Ghanam; Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed. Sci. 2016, 2(2), 11-15. doi: 10.11648/j.bs.20160202.11

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    AMA Style

    Qingyu Cheng, Shengwei Ke, A. R. Ghanam, Xiaoyuan Song. LncRNAs: The Ideal Composer of the Melody for Life. Biomed Sci. 2016;2(2):11-15. doi: 10.11648/j.bs.20160202.11

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  • @article{10.11648/j.bs.20160202.11,
      author = {Qingyu Cheng and Shengwei Ke and A. R. Ghanam and Xiaoyuan Song},
      title = {LncRNAs: The Ideal Composer of the Melody for Life},
      journal = {Biomedical Sciences},
      volume = {2},
      number = {2},
      pages = {11-15},
      doi = {10.11648/j.bs.20160202.11},
      url = {https://doi.org/10.11648/j.bs.20160202.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20160202.11},
      abstract = {Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - LncRNAs: The Ideal Composer of the Melody for Life
    AU  - Qingyu Cheng
    AU  - Shengwei Ke
    AU  - A. R. Ghanam
    AU  - Xiaoyuan Song
    Y1  - 2016/06/30
    PY  - 2016
    N1  - https://doi.org/10.11648/j.bs.20160202.11
    DO  - 10.11648/j.bs.20160202.11
    T2  - Biomedical Sciences
    JF  - Biomedical Sciences
    JO  - Biomedical Sciences
    SP  - 11
    EP  - 15
    PB  - Science Publishing Group
    SN  - 2575-3932
    UR  - https://doi.org/10.11648/j.bs.20160202.11
    AB  - Long noncoding RNAs (lncNRAs), as major transcripts from the genome, are becoming indispensable keys to invisible doors linking to a new horizon, prompting a shift in the previous thoughts that lncRNAs are the transcriptional noises and by-products. The most puzzling fact, however, is that in spite of their pervasive regulation of many biological processes and diverse human diseases, their exact functions are still unclear. Here we review the regulations by lncRNAs at different levels, revealing some insights upon the molecular mechanisms and pathogenesis of related diseases.
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China

  • CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China

  • CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China

  • CAS Key Laboratory of Brain Function and Disease, CAS Center for Excellence in Molecular Cell Science, School of Life Sciences, University of Science and Technology of China, Hefei, China

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