Applications of Molecularly Imprinted Polymers in Biochemistry
01About This Special Issue
Molecularly imprinted polymers (MIPs), so-called “artificial antibodies”, are a type of selective materials that possess binding sites and exhibit high selectivity and affinity toward a target compound (template). MIPs are usually synthesized by polymerization of a functional monomer and a target compound (template) in the presence of a cross-linker. MIPs are easy to prepare, stable at harsh operating conditions, inexpensive, reusable and capable of selective recognition of target compounds. MIPs function as a novel type of solid phase extraction (SPE) materials with improved selectivity and efficiency compared to traditional SPE materials, such as silica or polymers.MIPs are also used in biosensors as recognition units. MIPs can recognize target analytes not only by their shape and size, because introducing a dedicated set of recognizing sites into the imprinted cavity increases both the affinity of the cavity for the analyte and its selectivity with respect to interferences.
MIP-based enzyme-like catalysts (artificial enzymes) are another application of MIPs in biomimetic catalysis. For the preparation of MIP-based artificial enzymes, the functional monomers are incorporated in the polymeric structure by choosing the substrate of desired enzyme or the transition state analogue of the reaction as the template compound.
This special issue aims to provide a comprehensive collection of original research articles on the design and preparation of novel MIPs as SPE resins, biosensor platforms and artificial enzymes.
Aims and Scope:
Design and preparation of molecularly imprinted polymers (MIPs) for SPE applications
SPE of biomolecules by using MIPs
Design and preparation of MIPs for sensor applications
MIP-based artificial enzymes
MIP nanoparticles
MIP nanocomposites
02Meet the Guest Editors
Our distinguished editors bring deep subject-matter expertise to curate high-quality research and ensure a rigorous peer-review process.
Lead Guest Editor
Rustem Kecili
Department of Medical Services and Techniques, Anadolu University /Yunus Emre Vocational School, Eskisehir, Turkey
Guest Editor
Phanindhar Shivapooja
Intel Corporation, Hillsboro, United States
Guest Editor
Rajesh Pandiyan
Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Chennai, India
ORCID
Guest Editor
Rüstem Keçili
Department of Medical Services and Techniques/Yunus Emre Vocational School, Anadolu University, Eskişehir, Turkey
Guest Editor
Emine Çelikoğlu
Department of Biology/Faculty of Science, Anadolu University, Eskişehir, Turkey
Guest Editor
Umut Çelikoğlu
Department of Chemistry, Faculty of Science, Anadolu University, Eskişehir, Turkey
Guest Editor
Ebrahim Talebi
Department of Animal Science, Islamic Azad University, Darab, Iran
