Cell Biology

Volume 2, Issue 3, May 2014

  • Genotoxic and Histopathological Aspects of Treatment with Grape Seed Extract on Cancer Induced with Cyclophosphamide in Mice

    Ezzat I. Aboul-ela, Enayat A. Omara

    Issue: Volume 2, Issue 3, May 2014
    Pages: 18-27
    Received: 2 July 2014
    Accepted: 18 July 2014
    Published: 30 July 2014
    Abstract: Cyclophosphamide (CP) is an alkylating agent widely used in cancer chemotherapy. The present study was undertaken to evaluate the natural protective efficacy of methanolic grape seed extract (GSE) against CP-induced genotoxicity and histopathologically changes of liver and colon cancer cells in mice. After the mice were sacrificed on day 30 liver a... Show More