Research Article
Long-Term Mortality of Hemorrhagic Stroke Survivors in Bobo-Dioulasso, Burkina Faso: A Retrospective
Hospital-Based Cohort Study
Ouedraogo Pingdewende Victor*
,
Drave Alassane,
Boudzoumou Diagambana Bertandrie Estelle,
Savadogo Abdoul Aziz,
Ouedraogo Abaz,
Kagone Amos Wendyam,
Napon Christian
Issue:
Volume 10, Issue 3, September 2026
Pages:
71-76
Received:
12 June 2026
Accepted:
2 July 2026
Published:
24 July 2026
Abstract: Introduction. Long-term survival of hemorrhagic strokes remains poorly evaluated in our context. They represent the most severe type of stroke, accounting for 10 to 20% of all stroke cases. These rates are elevated in sub-Saharan Africa, potentially accounting for as much as 35% of all strokes. This study’s purpose was to analyze the long-term mortality of stroke survivors at the Souro Sanou University Hospital in Bobo-Dioulasso. Methods. This was a retrospective cohort of patients hospitalized from January 1, 2017 to December 31, 2019, discharged alive from the neurology department after haemorrhagic stroke. Data were analyzed using STATA 17.0 software. The 4-year survival probability was estimated. Predictors of mortality were identified using Cox regression. Results. A total of 57 patients were involved in this study. The mean age was 58.4 years (±12.4). The sex ratio was 1.19. Hypertension was the main cardiovascular risk factor (71.9%). Four patients had a history of heart disease. The level of consciousness was normal in 50 patients. The average length of hospital stay was 11.3 days. Cumulative post-hospital mortality was 21.1% at 4 years. Predictors of mortality were Glasgow coma scale>9 (p=0.001; HR = 0.09; CI 95%: 0.02-0.40) and presence of heart disease (p=0.015; HR = 5.87; CI 95%: 1.42-24.29). Conclusion. The long-term mortality associated with haemorrhagic stroke is high. Targeted interventions such as specialist hypertension clinics, cardiological follow-up and structured outpatient programmes could improve this long-term mortality considerably.
Abstract: Introduction. Long-term survival of hemorrhagic strokes remains poorly evaluated in our context. They represent the most severe type of stroke, accounting for 10 to 20% of all stroke cases. These rates are elevated in sub-Saharan Africa, potentially accounting for as much as 35% of all strokes. This study’s purpose was to analyze the long-term mort...
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Review Article
Lytico-Bodig in Guam: A Mysterious Neurological Disease
Issue:
Volume 10, Issue 3, September 2026
Pages:
77-82
Received:
13 June 2026
Accepted:
7 July 2026
Published:
11 August 2026
DOI:
10.11648/j.cnn.20261003.12
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Abstract: Lytico-Bodig disease, also known as Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex (ALS-PDC), is a rare neurodegenerative disorder uniquely affecting the Chamorro people of Guam. This review analyzes its historical context, epidemiology, clinical features, proposed causes, and ongoing research. First identified in the mid-20th century, Lytico-Bodig combines ALS-like motor symptoms, parkinsonism, and dementia, with notable clinical variability. It disproportionately affects certain Chamorro families and villages, suggesting genetic and environmental influences. The disease peaked in the 1950s–60s as a leading cause of death. Although the incidence has dramatically declined, cases persist, reflecting its public health relevance. While environmental factors, notably cycad seeds and flying foxes containing the neurotoxin β-methylamino-L-alanine (BMAA), along with genetic susceptibility are strongly implicated, the causal link between BMAA and the disease remains a subject of ongoing scientific debate and uncertainty. Neuropathological findings show neuronal loss, tau protein deposits, and neurofibrillary tangles, similar to Alzheimer’s and Parkinson’s diseases. Diagnosis is difficult due to symptom overlap with other conditions, and treatment remains supportive. Its progressive nature imposes a heavy burden on caregivers, underscoring the need for robust support systems. Ultimately, Lytico-Bodig remains a complex disorder requiring continued research, improved healthcare strategies, and community involvement to improve outcomes for affected individuals.
Abstract: Lytico-Bodig disease, also known as Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex (ALS-PDC), is a rare neurodegenerative disorder uniquely affecting the Chamorro people of Guam. This review analyzes its historical context, epidemiology, clinical features, proposed causes, and ongoing research. First identified in the mid-20th century,...
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