American Journal of Life Sciences

Volume 7, Issue 1, February 2019

  • Role of Health Extension Worker in Tuberculosis Prevention and Control in Ethiopia: Systematic Review

    Tesfaye Dagne Weldemarium, Muluneh Getachew

    Issue: Volume 7, Issue 1, February 2019
    Pages: 1-4
    Received: Dec. 11, 2018
    Accepted: Jan. 24, 2019
    Published: Feb. 21, 2019
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    Abstract: Background: Health Extension Program was designed to serve the rural community of Ethiopia and has brought significant change in improving utilization of family planning, antenatal care, postnatal care, birth preparedness, initiating breast feeding immediately after birth and HIV testing. In relation to Tuberculosis (TB) prevention and control, TB ... Show More
  • Serum Chymotrypsin-Like Activity on Digestion of Ala-Ala-AMC as a Substrate, Among CML and AML Patients at TASH, Addis Ababa Ethiopia: A Comparative Cross-Sectional Study

    Endriyas Kelta Wabalo, Abdulaziz Abubeker, Chala Kenenisa Edae, Belay Zawdie

    Issue: Volume 7, Issue 1, February 2019
    Pages: 5-11
    Received: Dec. 25, 2018
    Accepted: Feb. 07, 2019
    Published: Feb. 25, 2019
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    Abstract: Proteosome, composed of 19S and 20S subunits, is vital for AML and CML cell cycling, proliferation, adhesion and as a means to by-pass apoptosis through three distinguishable proteolytic activities. Chymotrypsin-like (CT-L) activity is rate limiting and a well-established therapeutic strategy for AML and CML cells, by proteosome inhibitors than the... Show More
  • Risk Factors of Elderly Type 2 Diabetes Mellitus Complicated with Osteoporosis and Effects of Vitamin K1 on Bone Mineral Density and Insulin Resistance

    Lei Sun, Hongjian Yu, Donghui Tian, Rui Zhang, Wenjing Du

    Issue: Volume 7, Issue 1, February 2019
    Pages: 12-16
    Received: Jan. 22, 2019
    Accepted:
    Published: Mar. 08, 2019
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    Abstract: Aim: To analyze the bone mineral density (BMD) changes of type 2 diabetes mellitus (T2DM) after being complicated with osteoporosis (OP) and their correlations with multiple risk factors. Methods: 240 cases of elderly T2DM patients were divided into an OP group and a non-OP group according to the BMD values. The results were subjected to correlatio... Show More
  • Soil Fauna as Webmasters, Engineers and Bioindicators in Ecosystems: Implications for Conservation Ecology and Sustainable Agriculture

    Sefi Mekonen Ertiban

    Issue: Volume 7, Issue 1, February 2019
    Pages: 17-26
    Received: Jan. 24, 2019
    Accepted: Mar. 14, 2019
    Published: Apr. 09, 2019
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    Abstract: Soil biodiversity comprised the organisms that spend all or a portion of their life cycles within the soil or on its immediate surface. Soil Fauna are those organisms that inhabit the soil (include arthropods, nematodes, molluscs, protozoa, rotifera, etc...). Of the total diversity of living organisms that has been described to date, 23% is soil an... Show More
  • Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism

    Xu Qian, Zhang Jing-yu, Li Hong-yan, Hou Jian-zhang

    Issue: Volume 7, Issue 1, February 2019
    Pages: 27-30
    Received: Feb. 26, 2019
    Accepted:
    Published: Apr. 28, 2019
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    Abstract: [Objective] To discuss the changes of endothelin (ET), homocysteine (Hcy) and blood lipids levels in patients with hyperthyroidism and subclinical hyperthyroidism, and to explore their clinical significance. [Methods] The authors choose 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of the control group to test... Show More
  • ANXA5 Enhances Malignancy of Murine Hepatocarcinoma Hca-P Cells via ERK Activation and E-cadherin Suppression

    Shuqing Liu, Chen Chen, Mingzhong Sun

    Issue: Volume 7, Issue 1, February 2019
    Pages: 31-37
    Received: Apr. 02, 2019
    Accepted:
    Published: May 23, 2019
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    Abstract: The invasion and metastasis are linked to the rapid progression and poor prognosis of hepatocarcinoma patients. Lymphatic metastasis is potentially involved in above pathogenesis with unclear mechanism. Previously, we found the deregulation of annexin A5 (ANXA5), a member of Ca2+-regulated phospholipid- and membrane-binding annexin family protein, ... Show More