International Journal of Clinical and Experimental Medical Sciences

Volume 7, Issue 4, July 2021

  • The Relationship of Changes in the Planet's Biosphere with the COVID-19 Pandemic and the Foundations of the Physical Theory of Virus Expansion

    Evgeniy Shirokov

    Issue: Volume 7, Issue 4, July 2021
    Pages: 74-80
    Received: May 22, 2021
    Accepted: Jun. 07, 2021
    Published: Jul. 02, 2021
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    Abstract: In recent decades, epidemics of new, previously unknown human viral diseases, and their number is growing. The COVID-19 pandemic caused by the SARS-CoV-2 showed that the humanity is not prepared to deal with new challenges and does not understand the causes of aggression of viruses at all. An attempt to explain the catastrophic spread of the new co... Show More
  • Microvascular Angina, on the Purpose of a Case from Southern Colombian

    Santiago Emilio Campbell Silva, Carlos Hernan Calderon Franco, Diego Julian Alvis Pena, Juan David Bermeo Calderón, Luis Carlos Altahona Escobar, Díana Lizeth Grajales Trujillo, Lina Maria Gonzalez Vargas

    Issue: Volume 7, Issue 4, July 2021
    Pages: 81-85
    Received: May 01, 2021
    Accepted: May 25, 2021
    Published: Jul. 09, 2021
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    Abstract: The most common cause of myocardial ischemia and angina is coronary stenosis by atheromatous lesions in the epicardial arteries. However, a significant percentage of patients with angina and ischemia demonstrated by tests to induce it not present coronary obstructions on angiography. For this reason, the case of a 68-year-old woman is presented, wh... Show More
  • The Conceptual Mapping and Its Importance in Nursing Education and Practice

    Usha Rani Kandula, Addisu Dabi Wake

    Issue: Volume 7, Issue 4, July 2021
    Pages: 86-90
    Received: May 13, 2021
    Accepted: Jul. 02, 2021
    Published: Jul. 09, 2021
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    Abstract: Conceptual maps are observed as new and efficient teaching and learning tools for the student learning process. These maps are educational useful tools for teachers and learners; it creates significant knowledge on a specific subject and represents it in a schematic manner. Concept maps are one of the significant teaching methods that support learn... Show More
  • New Generation Sequencing in Cholangiocarcinoma and Gallbladder Cancer: Clinical Implications for Immunotherapy

    Hao Song, Hongyan Ma, Yao Huang, Bin Yi, Xiaoqing Jiang

    Issue: Volume 7, Issue 4, July 2021
    Pages: 91-97
    Received: Jun. 20, 2021
    Accepted: Jul. 08, 2021
    Published: Jul. 16, 2021
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    Abstract: Objective: To explore the common mutation gene and mutation rule of cholangiocarcinoma and gallbladder cancer, and to confirm the therapeutic effect of PD1 inhibitor through follow-up. Method: From 2017 to 2019, 42 patients with intrahepatic cholangiocarcinoma (ICCA), 49 patients with extrahepatic cholangiocarcinoma (ECCA) and 40 patients with GBC ... Show More
  • Experimental Mechanical Jaundice: Morphological Aspects of Proliferation, the Possibility of Transformation and Involution of Epithelial Cells in the Bile Ducts

    Asomidin Faizovich Sadriddinov, Sheraliev Kambarali Saidalievich, Hidirova Gulnoza Azodovna, Muborak Asomidinovna Sadriddinova, Elena Nikolaevna Guzacheva

    Issue: Volume 7, Issue 4, July 2021
    Pages: 98-102
    Received: Jun. 08, 2021
    Accepted: Jul. 08, 2021
    Published: Jul. 24, 2021
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    Abstract: On an experimental model of obstructive jaundice in experimental rats, the cytological aspects of proliferation and the possibility of transformation of cholangiol cells into hepatocytes, as well as the cellular mechanisms of involution of the bile ducts, were investigated. The material was the liver of sexually mature rats (n=38) with 10, 20, and ... Show More
  • Effect of Cutaneous Leishmaniasis on Quality of Life of Patients, a Multicentric Study in Tertiary Care Hospitals in Pakistan Using DLQI

    Najia Ahmed, Aymen Naeem, Bisma Zahid, Moizza Tahir, Uzma Bashir, Sameena Kausar, Omer Farooq, Saira Ahmed

    Issue: Volume 7, Issue 4, July 2021
    Pages: 103-107
    Received: Jun. 13, 2021
    Accepted: Jul. 19, 2021
    Published: Jul. 27, 2021
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    Abstract: Cutaneous Leishmaniasis (CL) is a disease caused by the parasite “Leishmania” and is endemic in more than 90 countries of the world. Despite its vast prevalence and impact on quality of life (qol), it is one of the most neglected tropical dermatological diseases. The patients face considerable mental challenges including anxiety, depression and low... Show More
  • A Qualitative Research of Cancer Patients' Experience of Participating in Shared Decision-Making

    Huei-Lan Chang, Chiou-Fen Lin

    Issue: Volume 7, Issue 4, July 2021
    Pages: 108-114
    Received: Jun. 27, 2021
    Accepted: Jul. 20, 2021
    Published: Jul. 27, 2021
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    Abstract: Cancer is a life-threatening disease, albeit the continued improvement in treatment strategies, there are still many uncertainties during the treatment process and the effectiveness. In the current healthcare settings, shared decision-making (SDM) or patients’ preference and values and participation have less frequently been incorporated in the med... Show More
  • Rational Use of Antiviral Drugs Against SARS-CoV2

    Naiju Zhang, Tianping Chen, Kuihua Xu, Chuanmiao Liu, Shousong Zhao, Wei Li

    Issue: Volume 7, Issue 4, July 2021
    Pages: 115-119
    Received: Jul. 20, 2021
    Accepted: Aug. 09, 2021
    Published: Aug. 13, 2021
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    Abstract: Background: In December 2019, the outbreak of infectious pneumonia caused by a novel strain of coronavirus was named 'SARS-CoV2', which appeared in Wuhan, China. The said virus is highly contagious and rapidly spread across the world. So far, there is no effective antiviral drug in clinic. Objective: To make clinicians standardize the usage of the ... Show More
  • Progress in the Application of Single-cell Sequencing Technology in Cartilage Tissue Diseases

    Li Zhencong, Xu Yude, Wu Hao, Yao Yicun, Ye Dongping, Miao Haixiong, Liang Weiguo

    Issue: Volume 7, Issue 4, July 2021
    Pages: 120-126
    Received: Jul. 30, 2021
    Accepted: Aug. 10, 2021
    Published: Aug. 26, 2021
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    Abstract: Background: In the study of the pathogenesis of cartilage tissue (articular cartilage, meniscus, intervertebral disc, etc.) diseases, the most common research object is to explore some possible pathogenesis and pathogenesis in the direction of the whole pathological changes of these overall tissues. Therefore, there are many limitations and inaccur... Show More