Biochemistry and Molecular Biology

Volume 2, Issue 4, July 2017

  • Chemical Pathology of Chemerin and Its Link to Obesity and Type 2 Diabetes Mellitus: A Review

    Ekpe E. E., Ekpe V. E.

    Issue: Volume 2, Issue 4, July 2017
    Pages: 37-39
    Received: 29 April 2017
    Accepted: 1 June 2017
    Published: 14 July 2017
    Abstract: Adipocytokines have been widely recognized in scientific research in recent times because of their varied functions and roles in the body. One of such recognized adipocytokines, is chemerin. A review of chemerin, is presented in this paper with a view to assessing the pathophysiology involved in obesity and type 2 diabetes mellitus. Published liter... Show More
  • Review Paper on Approaches in Developing Inbred Lines in Cross-Pollinated Crops

    Aliyi Robsa Shuro

    Issue: Volume 2, Issue 4, July 2017
    Pages: 40-45
    Received: 2 May 2017
    Accepted: 17 May 2017
    Published: 24 July 2017
    Abstract: Plant breeding aims to constantly develop crop cultivars with improved yields and quality and tolerant to droughts, diseases and pests. Use of genetically improved crop cultivars and better management practices are among the best strategies to increase food production and meet a projected doubling of food demand. Inbred lines are homozygous genotyp... Show More
  • Inhibition of mRNA Maturation by Compounds Which Have a Flavonoid Skeleton

    Masashi Kurata, Mari Morimoto, Yuko Kawamura, Intisar Fouad Ali Mursi, Keiko Momma, Masakazu Takahashi, Yusaku Miyamae, Taiho Kambe, Masaya Nagao, Hiroshi Narita, Yasuyuki Shibuya, Seiji Masuda

    Issue: Volume 2, Issue 4, July 2017
    Pages: 46-53
    Received: 19 June 2017
    Accepted: 29 June 2017
    Published: 31 July 2017
    Abstract: Post-transcriptional modifications of nascent mRNA include 5’ capping, splicing and 3’ end polyadenylation, resulting in the emergence of mature mRNA. Recent findings indicate that mRNA splicing inhibitors can be potential anti-cancer candidates. Soy-isoflavone fractions displayed an inhibitory effect of mRNA processing among a number of dietary co... Show More