Biochemistry and Molecular Biology

Volume 4, Issue 3, May 2019

  • Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex

    Kudrat-E-Zahan, Saddam Hossain, M. M. Haque, Laila Arjuman Banu, M. A. Matin, Nur Amin Bitu, Ahsan Habib, Ashrafuzzaman, Nayon Uddin, M. S. Islam

    Issue: Volume 4, Issue 3, May 2019
    Pages: 35-41
    Received: 21 March 2019
    Accepted: 31 May 2019
    Published: 6 August 2019
    Abstract: Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics has dropped dramatically day by day. Metal complex [Co (SB) (SCN)] (where, SB = 2-[(6-Amino-hexylimino)-methyl] phenol) have been reported for the purpose of searching new antimicrobial agents. The Schiff base and it’s transition metal complex wa... Show More
  • Expression and Characterization of Manduca sexta Stress Responsive Peptide-1; An Inducer of Antimicrobial Peptide Synthesis

    Lynn Goss Schrag, Xiaolong Cao, Hawa Dembele, Xiaorong Liu, Qasim Al Souhail, Michael Robert Kanost, Jianhan Chen, Haobo Jiang, Om Prakash

    Issue: Volume 4, Issue 3, May 2019
    Pages: 42-52
    Received: 5 July 2019
    Accepted: 1 August 2019
    Published: 14 August 2019
    Abstract: In response to stress conditions such as wounding or infections in insects, several short peptides are processed to act as cytokines that induce AMP gene expression. To study their structure-activity relationship, immune inducibility, tissue specificity, stress responsiveness, and development relatedness, we chemically synthesized Manduca sexta str... Show More