Biochemistry and Molecular Biology

Volume 8, Issue 2, June 2023

  • Reactivity Skin-Prick Test with Common Allergens and Their Genetic Association with Polymorphisms in IL-9, IL-13, IL-4, IL-5 & IL-4Rα Genes among Asthmatics in Sudan

    Amel Osman Gundi, Fatima Omer Hamed, Maha Hassan Agraa, Hiba Salaheldin Mohamed

    Issue: Volume 8, Issue 2, June 2023
    Pages: 21-28
    Received: 17 March 2023
    Accepted: 16 May 2023
    Published: 5 June 2023
    Abstract: Atopy may be defined as the production of abnormal amounts of Immunoglobulin E (IgE) antibodies in response to aeroallergens, assessed by positive skin-prick test (SPT) responses. Allergic asthma is the result of a complex multifactorial interplay between genes and the environment. The interaction of genetic and environmental factors may increase t... Show More
  • The ACE 2 G8790A and IL-22 Gene Polymorphisms and their Association with Susceptibility to COVID-19 in Yaounde, Cameroon

    Calvino Fomboh Tah, Akindeh Mbuh Nji, Jean Paul Kengne Chedjou, Lesley Ngum Ngum, Carine Nguefeu Nkenfou Tchinda, Rhoda Bongshe Laban, Cyrille Mbanwi Mbu’u, MacDonald Bin Eric, Palmer Masumbe Netongo, Tatiana Tchakote Wami, Wilfried Olivier Ngandjeu Tchamdjeu, Marie Claire Vernyuy Fonyuy, Wilfred Fon Mbacham

    Issue: Volume 8, Issue 2, June 2023
    Pages: 29-36
    Received: 4 August 2023
    Accepted: 21 August 2023
    Published: 8 September 2023
    Abstract: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus that replicates in the cytoplasm, and uses envelope spike projections as a key to enter to human cells with the receptor. Host susceptibility upon exposure to the virus might be as a result of genetic polymorphisms observed on genes that encode... Show More