Biochemistry and Molecular Biology

Volume 8, Issue 3, September 2023

  • Research Article

    NLRP3 Gene Polymorphisms and Association with Type 2 Diabetes mellitus and Malaria Co-morbidity in Yaounde, Cameroon

    Marie-Claire Vernyuy Fonyuy, Calvino Fomboh Tah, Akindeh Mbuh Nji, Isabelle Mboutchuin Kamdem Winnie, Jean Paul Kengne Chedjou, Magellan Guewo Fokeng, Aristid Herve Ekollo Mbange, Wilfried Olivier Ngandjeu Tchamdjeu, Lesley Ngum Ngum, Peter Thelma Ngwa Niba, Rodrigue Essomba Foe, Cedric Hermann Dongmo, Carine Nguefeu Nkenfou-Tchinda, Rhoda Bongshe Laban, Yusinyu Eugenie Mumah, Eugene Sobngwi, Jean Claude Mbanya, Wilfred Fon Mbacham*

    Issue: Volume 8, Issue 3, September 2023
    Pages: 37-44
    Received: 27 October 2023
    Accepted: 14 November 2023
    Published: 30 November 2023
    Abstract: Background: Diabetes is increasingly prevalent in malaria endemic settings like Cameroon thus contributing to a double burden in the management of these inflammatory diseases. Studies have shown that NLRP3 inflammasome plays a key role in type-2 diabetes (T2DM) and malaria induced inflammation. However, the hypothesis that the Single Nucleotides Po... Show More