Biochemistry and Molecular Biology

Volume 3, Issue 4, July 2018

  • Design, Synthesis and Biological Evaluation of Novel Osthole Derivatives as Potential Agents for the Treatment of Cancer

    Jing Liu, Qi He, Jiaoli Ding, Zhipeng Zhang, Weixin Zhou, Saisai Xie

    Issue: Volume 3, Issue 4, July 2018
    Pages: 56-62
    Received: 16 November 2018
    Accepted: 6 December 2018
    Published: 18 December 2018
    Abstract: Aim: Osthole, an ingredient of Traditional Chinese Medicine (TCM) from natural product Cnidium monnieri (L.) Cusson, showed many biological activities related to the treatment of cancer. However, the comparatively weak activity hinders its further application in clinical. Therefore, the aim of the present study was design and synthesis of a series ... Show More