Biochemistry and Molecular Biology

Volume 10, Issue 2, June 2025

  • Research Article

    Tumor-Targeted Folic Acid-Modified Porfimer Conjugated Poly (Ethylene Glycol) Nanoparticles for Radiosensitized Treatment of Cancer

    Song-Jin Pak, Chang-Jun Kim, Kwang-Il To*, Nam-Hyok Ooh, Mun-Hyok Ri, Chol-Ho Ri, Nam-Yong Kim

    Issue: Volume 10, Issue 2, June 2025
    Pages: 20-28
    Received: 7 April 2025
    Accepted: 29 April 2025
    Published: 12 June 2025
    DOI: 10.11648/j.bmb.20251002.11
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    Abstract: Folic acid-modified porfimer conjugated poly (ethylene glycol) nanoparticles (FPP NPs), as the novel radiosensitizer, for tumor-targeted radiosensitized treatment (RST) were synthesized and characterized. Diamino poly (ethylene glycol) was covalently conjugated with folic acid and porfimer (also known as photofrin) in its terminal ends and self-ass... Show More